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pentobarbital will reduce the level or impact of gefitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will reduce the extent or impact of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir can be reduced if coadministered with s